Determination of co-administrated opioids and benzodiazepines in urine using column-switching solid-phase extraction and liquid chromatography-tandem mass spectrometry.

Abstract

Co-administration of opioids with benzodiazepines is very common around the world. A semi-automated method was developed for the determination of four opioids and two benzodiazepines as well as their metabolites (including glucuronide metabolites) in human urine, based on on-line column-switching-solid-phase extraction (CS-SPE) and liquid chromatography… (More)
DOI: 10.1016/j.chroma.2015.03.064

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Cite this paper

@article{Xiong2015DeterminationOC, title={Determination of co-administrated opioids and benzodiazepines in urine using column-switching solid-phase extraction and liquid chromatography-tandem mass spectrometry.}, author={Lingjuan Xiong and Rong Wang and Chen Liang and Xiaomei Teng and Fengli Jiang and Libo Zeng and Haiying Ye and Chunfang Ni and Xiaoliang Yuan and Yulan Rao and Yurong Zhang}, journal={Journal of chromatography. A}, year={2015}, volume={1395}, pages={99-108} }