Determination of carotenoid stereoisomers in commercial dietary supplements by high-performance liquid chromatography.

@article{Aman2004DeterminationOC,
  title={Determination of carotenoid stereoisomers in commercial dietary supplements by high-performance liquid chromatography.},
  author={Robert Aman and Sandra Bayha and Reinhold Carle and Andreas Schieber},
  journal={Journal of agricultural and food chemistry},
  year={2004},
  volume={52 20},
  pages={6086-90}
}
A method for the determination of beta-carotene, lutein, and zeaxanthin including their cis-isomers and alpha-carotene in commercial dietary supplements by HPLC has been developed. The study comprises 11 oral dosage forms, including 9 soft gelatin capsules, 1 dragée, and 1 effervescent tablet formulation. The capsule content was extracted with an acetone-hexane mixture, and the gelatin shell was digested with papain to release carotenoids that had migrated into the coat. Sample preparation for… CONTINUE READING

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