Determination of berberine in human plasma by liquid chromatography-electrospray ionization-mass spectrometry.

Abstract

A liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) method for the determination of berberine in human plasma using chlorobenzylidine as the internal standard (IS) has been developed and validated. The plasma samples were prepared by LLE and the analytes were chromatographically separated on a Hanbon Lichrospher 5-C18 HPLC column… (More)

Topics

Cite this paper

@article{Hua2007DeterminationOB, title={Determination of berberine in human plasma by liquid chromatography-electrospray ionization-mass spectrometry.}, author={Wenyan Hua and Li Ding and Yan Chen and Bin Gong and Jianchang He and Guili Xu}, journal={Journal of pharmaceutical and biomedical analysis}, year={2007}, volume={44 4}, pages={931-7} }