Determination of apparent association constants of steroid-cyclodextrin inclusion complexes using a modification of the Hummel-Dreyer method.

@article{Flood2001DeterminationOA,
  title={Determination of apparent association constants of steroid-cyclodextrin inclusion complexes using a modification of the Hummel-Dreyer method.},
  author={Kelliel Flood and Evan R. C. Reynolds and Nicholas H. Snow},
  journal={Journal of chromatography. A},
  year={2001},
  volume={913 1-2},
  pages={261-8}
}
A modified Hummel-Dreyer method was used to calculate the apparent association constants of steroid-cyclodextrin inclusion complexes. An external calibration technique was employed, using the y-intercept from a plot of peak area versus concentration to correct for sample solvent effects. Mobile phase temperature and sample diluent organic content were found to be critical factors affecting the accuracy and reproducibility of the results. For four of six sets of data, the modified Hummel-Dreyer… CONTINUE READING

From This Paper

Topics from this paper.
2 Citations
0 References
Similar Papers

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…