Determination of antibody responses of elderly adults to all 23 capsular polysaccharides after pneumococcal vaccination.

@article{Rubins1999DeterminationOA,
  title={Determination of antibody responses of elderly adults to all 23 capsular polysaccharides after pneumococcal vaccination.},
  author={Jeffrey B. Rubins and Milton Alter and Joan Loch and Edward N. Janoff},
  journal={Infection and immunity},
  year={1999},
  volume={67 11},
  pages={
          5979-84
        }
}
The 23-valent pneumococcal polysaccharide vaccine was formulated to prevent invasive infection in the elderly and other high-risk populations from the most prevalent Streptococcus pneumoniae serotypes. However, the immunogenicity of all 23 vaccine polysaccharides has not been fully characterized in elderly adults. We previously reported that whereas the majority of elderly subjects had vigorous immune responses to selected pneumococcal vaccine polysaccharides, a subset of elderly individuals… CONTINUE READING
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