Determination of amosulalol in human plasma using solid-phase extraction combined with liquid chromatography and ultraviolet detection.


Amosulalol is an antihypertensive drug with selective postsynaptic alpha 1 and non-selective beta blocking effects. A simple solid-phase extraction and high-performance liquid chromatographic (HPLC) method has been developed and validated for the quantitative determination of amosulalol in human plasma. A reversed phase C18 column was used for the… (More)


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