Determination of advanced glycation endproducts by LC-MS/MS in raw and roasted almonds (Prunus dulcis).

  title={Determination of advanced glycation endproducts by LC-MS/MS in raw and roasted almonds (Prunus dulcis).},
  author={Gong Zhang and Guangwei Huang and Lu Xiao and Alyson E Mitchell},
  journal={Journal of agricultural and food chemistry},
  volume={59 22},
A sensitive and reliable LC-(ESI)MS/MS method was developed and validated for the simultaneous analysis of five common advanced glycation endproducts (AGEs) after enzymatic digestion in raw and roasted almonds. AGEs included carboxymethyl-lysine (CML), carboxyethyl-lysine (CEL), pyralline (Pyr), argpyrimidine (Arg-p), and pentosidine (Pento-s). This method allows accurate quantitation of free and AGE-protein adducts of target AGEs. Results indicate that CML and CEL are found in both raw and… CONTINUE READING
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