Determination of acetaminophen in human plasma by ion-pair reversed-phase high-performance liquid chromatography. Application to a single-dose pharmacokinetic study.

@article{Rustum1989DeterminationOA,
  title={Determination of acetaminophen in human plasma by ion-pair reversed-phase high-performance liquid chromatography. Application to a single-dose pharmacokinetic study.},
  author={Abu M Rustum},
  journal={Journal of chromatographic science},
  year={1989},
  volume={27 1},
  pages={18-22}
}
  • Abu M Rustum
  • Published 1989 in Journal of chromatographic science
The determination of acetaminophen in biological samples of humans who have ingested normal and overdosage of the drug is necessary to understand the clinical pharmacokinetics of acetaminophen and to determine its distribution and toxicokinetic parameters. This paper describes a rapid, simple, and sensitive high-performance liquid chromatographic method for… CONTINUE READING