Determination of VEGFR-2 (KDR) -604A>G polymorphism in recurrent pregnancy loss.

  title={Determination of VEGFR-2 (KDR) -604A>G polymorphism in recurrent pregnancy loss.},
  author={Lidia Boldeanu and Cristian A Siloşi and Vlad Pădureanu and Anda Lorena Dijmărescu and Maria Magdalena Manolea and Maria Carmen Tabacu and Mihail Virgil Boldeanu and Mircea Vasile Popescu-Drigă and Ioan Sabin Poenariu and Rodica Pădureanu and Liliana Novac and Marius Bogdan Novac},
  journal={Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie},
  volume={59 4},
BACKGROUND Placental angiogenesis and vascular adaptation during pregnancy, along with diminished placental trophoblastic vascular endothelial growth factor immunoreactivity, play an important role in the early stages of human pregnancy, being possible causes of recurrent pregnancy loss (RPL). AIMS Our focus was directed towards investigating a possible association between vascular endothelial growth factor receptor-2 (kinase insert domain receptor) VEGFR-2 (KDR) -604A>G (rs 2071559) gene… CONTINUE READING


Publications referenced by this paper.

Vascular endothelial growth factor gene 1154 G / A , 2578 C / A , 460 C / T , 936 C / T polymorphisms and association with recurrent pregnancy losses

S Aggarwal, F Parveen, +3 authors S Agrawal
  • Genet Mol Res
  • 2012