Determination of Regimes for Diphtheria Exotoxin Modification by Chemical and Physicochemical

@inproceedings{METHODS2011DeterminationOR,
  title={Determination of Regimes for Diphtheria Exotoxin Modification by Chemical and Physicochemical},
  author={METHODS and Babych and Kalinichenko and Ryzhkova and Pluhator},
  year={2011}
}
  • METHODS, Babych, +2 authors Pluhator
  • Published 2011
At the present stage of immunobiological industry development unsafeness of many vaccine preparations is associated with the presence of harmful substances, which are used for detoxification and subsequent storage of the substrate and with the presence of ballast proteins, which can cause formation of nonspecific antibodies and reinforce reactogenicity of preparations and their sensitizing properties during immunization. Nowadays toxoids are obtained by the addition of 0.6-1.5 per cent of… CONTINUE READING