Determination of Mexiletine in Pharmaceutical Preparations by Gas Chromatography with Flame Ionization Detection


A simple and rapid method for determination of mexiletine in pharmaceutical preparations was developed and validated using gas chromatography with flame ionization detection (GC-FID). GC separation was performed in about 5 min using a HP-5 capilary column (30 m x 0.320 mm, 0.25μm). Nitrogen was used as carrier gas at a flow-rate of 2 mL min. After injection… (More)


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