Determination of HCV genotype by direct sequence analysis of quantitative PCR products.

@article{Gargiulo2003DeterminationOH,
  title={Determination of HCV genotype by direct sequence analysis of quantitative PCR products.},
  author={Franco Gargiulo and Maria Antonia De Francesco and Gabriele Pinsi and Caterina Patrizia Pollara and Luigina Terlenghi and Francesca Perandin and N. del Valle Manca},
  journal={Journal of medical virology},
  year={2003},
  volume={69 2},
  pages={
          202-6
        }
}
Hepatitis C virus (HCV) genotyping, combined with quantitative evaluation of HCV RNA, may be beneficial for the management of chronic hepatitis C and in the selection of candidates for interferon treatment. In this study, the COBAS AMPLICOR HCV MONITOR test, a commercially available quantitative assay for HCV RNA, was used. Amplification products obtained from HCV-positive cases were subjected to direct sequencing and genotyping based on seven phylogenetically informative regions within the 5… CONTINUE READING
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