Determination of DNA and RNA Methylation in Circulating Tumor Cells by Mass Spectrometry.

@article{Huang2016DeterminationOD,
  title={Determination of DNA and RNA Methylation in Circulating Tumor Cells by Mass Spectrometry.},
  author={Wei Huang and Chu-Bo Qi and Song-Wei Lv and Min Xie and Yu-Qi Feng and Weihua Huang and Bi-Feng Yuan},
  journal={Analytical chemistry},
  year={2016},
  volume={88 2},
  pages={1378-84}
}
DNA methylation (5-methylcytosine, 5-mC) is the best characterized epigenetic mark that has regulatory roles in diverse biological processes. Recent investigation of RNA modifications also raises the possible functions of RNA adenine and cytosine methylations on gene regulation in the form of "RNA epigenetics." Previous studies demonstrated global DNA… CONTINUE READING