Determination of D-mannose in serum by capillary electrophoresis.

@article{Carchon2001DeterminationOD,
  title={Determination of D-mannose in serum by capillary electrophoresis.},
  author={H. Carchon and J. Jaeken},
  journal={Clinical chemistry},
  year={2001},
  volume={47 7},
  pages={
          1319-21
        }
}
  • H. Carchon, J. Jaeken
  • Published 2001
  • Medicine, Chemistry
  • Clinical chemistry
  • Congenital disorders of glycosylation (CDG) are a newly delineated group of inherited multisystem disorders associated with abnormal glycosylation of glycoproteins (1). In CDG group I, which includes all defects in N -glycan assembly (2), the subgroup CDG type Ib, attributable to phosphomannose isomerase (EC 5.3.1.8.) deficiency, is treatable by mannose supplementation (3). Monitoring of this treatment necessitates the availability of methods to quantify d-mannose in serum. The determination… CONTINUE READING

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