Determinants of weaning and survival among patients with COPD who require mechanical ventilation for acute respiratory failure.

@article{Menzies1989DeterminantsOW,
  title={Determinants of weaning and survival among patients with COPD who require mechanical ventilation for acute respiratory failure.},
  author={Richard Gordon Menzies and William B Gibbons and Peter Goldberg},
  journal={Chest},
  year={1989},
  volume={95 2},
  pages={
          398-405
        }
}
The decision to institute MV in patients with COPD and ARF is difficult because the risk of complications is high and the long-term prognosis is poor. We reviewed our experience with 95 COPD patients with ARF requiring MV. Fifty-five patients required MV for more than two weeks, 72 were weaned successfully, and 59 died within one year of follow-up. Survival was associated with premorbid level of activity (p less than .001), FEV1 (p less than .01), serum albumin level (p less than .05), and… CONTINUE READING

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