Determinants of virulence of influenza A virus

@article{Schrauwen2013DeterminantsOV,
  title={Determinants of virulence of influenza A virus},
  author={Eefje J. A. Schrauwen and Miranda de Graaf and Sander Herfst and Guus F Rimmelzwaan and Albert Dme Osterhaus and Ron A M Fouchier},
  journal={European Journal of Clinical Microbiology & Infectious Diseases},
  year={2013},
  volume={33},
  pages={479-490}
}
Influenza A viruses cause yearly seasonal epidemics and occasional global pandemics in humans. In the last century, four human influenza A virus pandemics have occurred. Occasionally, influenza A viruses that circulate in other species cross the species barrier and infect humans. Virus reassortment (i.e. mixing of gene segments of multiple viruses) and the accumulation of mutations contribute to the emergence of new influenza A virus variants. Fortunately, most of these variants do not have the… CONTINUE READING
BETA

Figures, Tables, and Topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
SHOWING 1-10 OF 17 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 108 REFERENCES

In vitro assessment of attachment pattern and replication efficiency of H5N1 influenza A viruses with altered receptor specificity

  • S Chutinimitkul, D van Riel, +6 authors E de Wit
  • J Virol
  • 2010
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…