Determinants of vancomycin clearance by continuous venovenous hemofiltration and continuous venovenous hemodialysis.

@article{Joy1998DeterminantsOV,
  title={Determinants of vancomycin clearance by continuous venovenous hemofiltration and continuous venovenous hemodialysis.},
  author={Melanie S Joy and Gary R. Matzke and R F Frye and Paul M Palevsky},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={1998},
  volume={31 6},
  pages={1019-27}
}
The clearance of vancomycin is significantly reduced in patients with acute, as well as, chronic renal failure. Although multiple-dosage regimen adjustment techniques have been proposed for these patients, there is little quantitative data to guide the individualization of vancomycin therapy in acute renal failure patients who are receiving continuous renal replacement therapy (CRRT). To determine appropriate vancomycin dosing strategies for patients receiving continuous venovenous… CONTINUE READING

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