Determinants of melanoma in a case–control study of twins (United States)

  title={Determinants of melanoma in a case–control study of twins (United States)},
  author={Myles Cockburn and William L. Black and Wendy McKelvey and Thomas J. Mack},
  journal={Cancer Causes & Control},
Objectives: To estimate the relative contribution of environmental and genetic factors disposing towards the development of melanoma. Methods: We investigated risk factors for melanoma in a case–control study conducted among 185 North American twin pairs in which one was diagnosed with melanoma and the other (the co-twin of the case) was not. We considered monozygous (MZ) and dyzygous (DZ) twins separately. Results: While greater risk of melanoma was associated with number of large nevi in DZ… CONTINUE READING

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