Determinants of hypercapnia in obese patients with obstructive sleep apnea: a systematic review and metaanalysis of cohort studies.

@article{Kaw2009DeterminantsOH,
  title={Determinants of hypercapnia in obese patients with obstructive sleep apnea: a systematic review and metaanalysis of cohort studies.},
  author={Roop Kaw and Adri{\'a}n V Hern{\'a}ndez and Esteban Walker and Loutfi S. Aboussouan and Babak Mokhlesi},
  journal={Chest},
  year={2009},
  volume={136 3},
  pages={787-796}
}
BACKGROUND Inconsistent information exists about factors associated with daytime hypercapnia in obese patients with obstructive sleep apnea (OSA). We systematically evaluated these factors in this population. METHODS We included studies evaluating the association between clinical and physiologic variables and daytime hypercapnia (Paco(2), >or= 45 mm Hg) in obese patients (body mass index [BMI], >or= 30 kg/m(2)) with OSA (apnea-hypopnea index [AHI], >or= 5) and with a < 15% prevalence of COPD… CONTINUE READING

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