Determinants of heat shock-induced chromosome puffing.


Modified Drosophila heat shock genes were introduced into the germ line by P element transformation. The genes were altered such that several factors could be tested for their influence upon chromosome puffing. Deletion of promoter sequences upstream of position -73 of an hsp70-IacZ hybrid gene was sufficient to abolish puffing. Analysis of progressive 5… (More)


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@article{Simon1985DeterminantsOH, title={Determinants of heat shock-induced chromosome puffing.}, author={Jeffrey A. Simon and Carola Ana Sutton and Robert B. Lobell and Robert L. Glaser and John T Lis}, journal={Cell}, year={1985}, volume={40 4}, pages={805-17} }