Determinants of health-related quality of life in pharmacoresistant epilepsy: results from a large multicenter study of consecutively enrolled patients using validated quantitative assessments.

@article{Luoni2011DeterminantsOH,
  title={Determinants of health-related quality of life in pharmacoresistant epilepsy: results from a large multicenter study of consecutively enrolled patients using validated quantitative assessments.},
  author={Chiara Luoni and Francesca Bisulli and Maria Paola Canevini and Giovambattista De Sarro and Cinzia Fattore and Carlo Andrea Galimberti and Giuliana Gatti and Angela la Neve and Giancarlo Muscas and Luigi Maria Specchio and Salvatore Striano and Emilio Perucca},
  journal={Epilepsia},
  year={2011},
  volume={52 12},
  pages={2181-91}
}
PURPOSE To evaluate the relative contribution of demographic and epilepsy-related variables, depressive symptoms, and adverse effects (AEs) of antiepileptic drugs (AEDs) to health-related quality of life (HRQOL) in adults with pharmacoresistant epilepsy. METHODS Individuals with epilepsy whose seizures failed to respond to at least one AED were enrolled consecutively at 11 tertiary referral centers. HRQOL was assessed by the Quality of Life in Epilepsy Inventory-31 (QOLIE-31), AEs by the… CONTINUE READING