Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.

@article{Jong1999DeterminantsOF,
  title={Determinants of fasting and post-methionine homocysteine levels in families predisposed to hyperhomocysteinemia and premature vascular disease.},
  author={Sylvia C de Jong and Coen D A Stehouwer and Martha van den Berg and Piet J. Kostense and David J. C. Alders and Carel Jakobs and Gerald Pals and Jan A. Rauwerda},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1999},
  volume={19 5},
  pages={1316-24}
}
Elevated plasma total homocysteine (tHcy) levels, either measured in the fasting state or after oral methionine loading, are associated with an increased risk of atherothrombotic disease. Fasting and post-methionine hyperhomocysteinemia (HHC) overlap to a limited extent; both can occur as familial traits. We investigated determinants of fasting, postmethionine and delta (ie, post-methionine minus fasting levels) tHcy levels in 510 subjects of 192 HHC-prone families including 161 patients with… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 51 references

High prevalence of hyperhomocysteinemia and asymptomatic vascular disease in siblings of young patients with vascular disease and hyperhomocysteinemia

SC De Jong, CDA Stehouwer, +5 authors JA. Rauwerda
Arterioscler Thromb Vasc Biol • 1997

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