Determinants of experimental allergic responses: interactions between allergen dose, sex and age.

@article{Hansen2011DeterminantsOE,
  title={Determinants of experimental allergic responses: interactions between allergen dose, sex and age.},
  author={Jitka Stilund Hansen and Torunn Alberg and Hanne Marie Skyggedal Rasmussen and Martinus Lovik and Unni Cecilie Nygaard},
  journal={Scandinavian journal of immunology},
  year={2011},
  volume={73 6},
  pages={554-67}
}
The prevalence of allergic diseases is influenced by sex and age. Although mouse models are widely used in allergy research, few experimental studies have examined the interaction effects of sex and age on allergy outcomes. Our aim was to investigate the individual and combined effects of sex and age on allergic sensitization and inflammation in two mouse models: an intraperitoneal (i.p.) and an intranasal (i.n.) sensitization model. We also investigated how the allergen immunization dose… CONTINUE READING