Determinants of exercise intolerance in patients with heart failure and reduced or preserved ejection fraction.

@article{Haykowsky2015DeterminantsOE,
  title={Determinants of exercise intolerance in patients with heart failure and reduced or preserved ejection fraction.},
  author={Mark J F Haykowsky and Corey R Tomczak and Jessica M Scott and David Ian Paterson and Dalane W. Kitzman},
  journal={Journal of applied physiology},
  year={2015},
  volume={119 6},
  pages={
          739-44
        }
}
This mini-review summarizes the literature regarding the mechanisms of exercise intolerance in patients with heart failure and reduced or preserved ejection fraction (HFREF and HFPEF, respectively). Evidence to date suggests that the reduced peak pulmonary oxygen uptake (pulm V̇o₂) in patients with HFREF compared with healthy controls is due to both central (reduced convective O₂ transport) and peripheral factors (impaired skeletal muscle blood flow, decreased diffusive O₂ transport coupled… CONTINUE READING

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SHOWING 1-10 OF 49 CITATIONS

Vascular Dysfunction in Heart Failure with Preserved Ejection Fraction.

  • Journal of cardiac failure
  • 2016
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CITES BACKGROUND & METHODS

Exercise Intolerance in Patients With Heart Failure: JACC State-of-the-Art Review.

  • Journal of the American College of Cardiology
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CITES BACKGROUND