Determinants of VO2 max decline with aging: an integrated perspective.

  title={Determinants of VO2 max decline with aging: an integrated perspective.},
  author={Andrew C. Betik and Russell T. Hepple},
  journal={Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme},
  volume={33 1},
  • A. Betik, R. Hepple
  • Published 4 January 2008
  • Biology
  • Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
Aging is associated with a progressive decline in the capacity for physical activity. Central to this decline is a reduction in the maximal rate of oxygen utilization, or VO2 max. This critical perspective examines the roles played by the factors that determine the rate of muscle oxygen delivery versus those that determine the utilization of oxygen by muscle as a means of probing the reasons for VO2 max decline with aging. Reductions in muscle oxygen delivery, principally due to reduced cardiac… 

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