Determinants of Renal Tissue Oxygenation as Measured with BOLD-MRI in Chronic Kidney Disease and Hypertension in Humans

@inproceedings{Pruijm2014DeterminantsOR,
  title={Determinants of Renal Tissue Oxygenation as Measured with BOLD-MRI in Chronic Kidney Disease and Hypertension in Humans},
  author={Menno Pruijm and Lucie Hofmann and Maciej Piskunowicz and M Muller and Carole Zweiacker and Isabelle Bassi and Bruno Vogt and M. Stuber and Michel Burnier},
  booktitle={PloS one},
  year={2014}
}
Experimentally renal tissue hypoxia appears to play an important role in the pathogenesis of chronic kidney disease (CKD) and arterial hypertension (AHT). In this study we measured renal tissue oxygenation and its determinants in humans using blood oxygenation level-dependent magnetic resonance imaging (BOLD-MRI) under standardized hydration conditions. Four coronal slices were selected, and a multi gradient echo sequence was used to acquire T2* weighted images. The mean cortical and medullary… CONTINUE READING