Determinants of Phagocytosis, Phagosome Biogenesis and Autophagy for Mycobacterium tuberculosis

@inproceedings{Schlesinger2017DeterminantsOP,
  title={Determinants of Phagocytosis, Phagosome Biogenesis and Autophagy for Mycobacterium tuberculosis},
  author={Larry S. Schlesinger and Abul Kalam Azad and Jordi B Torrelles and Esteban A Roberts and Isabelle Vergne and Vojo Deretic},
  year={2017}
}
Mycobacterium tuberculosis is an intracellular pathogen of mononuclear phagocytes and is highly adapted to the human host. This bacterium enters macrophages by the phagocytic process using a defined subset of receptors and subsequently multiplies within a unique phagosomal compartment. M. tuberculosis has developed multiple strategies to circumvent the normal fate of ingested pathogens both during and following phagocytosis. Evidence is emerging that surface mannosylation of M. tuberculosis… CONTINUE READING
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