Determinants for the repression of estrogen receptor transcriptional activity by ligand-occupied progestin receptors

@article{Kraus1997DeterminantsFT,
  title={Determinants for the repression of estrogen receptor transcriptional activity by ligand-occupied progestin receptors},
  author={W Lee Kraus and Karen E Weis and Benita S Katzenellenbogen},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={1997},
  volume={63},
  pages={175-188}
}
There is considerable evidence for cross-talk between the estrogen and progestin signaling pathways, including examples of repression or attenuation of estrogen-stimulated endpoints by progestin receptor (PR) agonists and antagonists. We have previously described an experimental system for examining aspects of this cross-talk, namely the repression of estrogen receptor (ER) transcriptional activity by liganded PR (Kraus, W. L., Weis, K. E., Katzenellenbogen, B. S., Mol. Cell. Biol. 15 (1995… CONTINUE READING

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