Determinants for Psychrophilic and Thermophilic Features of Metallopeptidases of the M4 Family

@article{Khan2009DeterminantsFP,
  title={Determinants for Psychrophilic and Thermophilic Features of Metallopeptidases of the M4 Family},
  author={Mahmud Tareq Hassan Khan and Ingebrigt Sylte},
  journal={In silico biology},
  year={2009},
  volume={9 3},
  pages={105-24}
}
Naturally occurring peptidases from organisms living under extreme conditions are adapted to function in environmental extremes, including temperature, salinity, pH, or pressure. These organisms represent unique sources for new bio-molecules that have both industrial and medicinal application. Adaptive strategies for functioning under extreme conditions are reflected at the enzyme sequence and structural level. Understanding the determinants responsible for unique functional features can be… CONTINUE READING