Determinants and prognostic value of Galectin-3 in patients with aortic valve stenosis.

  title={Determinants and prognostic value of Galectin-3 in patients with aortic valve stenosis.},
  author={Dimitri Arangalage and Virginia T Nguyen and Tiphaine Robert and Maria Melissopoulou and Tiffany Mathieu and Candice Estellat and Isabelle Codogno and Virginie Huart and Xavier Duval and Claire Cimadevilla and Alec S Vahanian and Monique Dehoux and David Messika-Zeitoun},
  volume={102 11},
OBJECTIVE Myocardial fibrosis has been proposed as an outcome predictor in asymptomatic patients with severe aortic stenosis (AS) that may lead to consider prophylactic surgery. It can be detected using MRI but its widespread use is limited and development of substitute biomarkers is highly desirable. We analysed the determinants and prognostic value of galectin-3, one promising biomarker linked to myocardial fibrosis. METHODS Patients with at least mild degenerative AS enrolled between 2006… CONTINUE READING
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