Determinants and impact of multidrug antibiotic resistance in pathogens causing ventilator-associated-pneumonia

  title={Determinants and impact of multidrug antibiotic resistance in pathogens causing ventilator-associated-pneumonia},
  author={Pieter O. Depuydt and Dominique Vandijck and Maarten A Bekaert and Johan Decruyenaere and Stijn Blot and Dirk Vogelaers and Dominique D Benoit},
  journal={Critical Care},
  pages={R142 - R142}
INTRODUCTION The idea that multidrug resistance (MDR) to antibiotics in pathogens causing ventilator-associated pneumonia (VAP) is an independent risk factor for adverse outcome is still debated. We aimed to identify the determinants of MDR versus non-MDR microbial aetiology in VAP and assessed whether MDR versus non-MDR VAP was independently associated with increased 30-day mortality. METHODS We performed a retrospective analysis of a prospectively registered cohort of adult patients with… CONTINUE READING


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Publications referenced by this paper.
Showing 1-10 of 44 references

A proportional hazards model for the subdistribution of a competing risk

  • J Fine, R Gray
  • J Am Statist Assoc
  • 1999
Highly Influential
9 Excerpts

Antimicrobial Key messages • The risk of MDR in VAP is especially high after exposure to more than two antibiotics

  • P Depuydt, S Blot, +6 authors F Colardyn
  • Crit Care Med
  • 2006
2 Excerpts

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