Determinant of cistron specificity in bacterial ribosomes

  title={Determinant of cistron specificity in bacterial ribosomes},
  author={John Shine and Lynn Dalgarno},
The sequence of the 3′-terminus of 16S RNA from different bacteria has been determined. Complementarity relationships between this sequence and a purine-rich tract in the ribosome binding site of different bacterial mRNAs suggest that the 3′-end of 16S RNA determines the intrinsic capacity of ribosomes to translate a particular cistron. 

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