Determinant of cistron specificity in bacterial ribosomes

@article{Shine1975DeterminantOC,
  title={Determinant of cistron specificity in bacterial ribosomes},
  author={John Shine and Lynn Dalgarno},
  journal={Nature},
  year={1975},
  volume={254},
  pages={34-38}
}
The sequence of the 3′-terminus of 16S RNA from different bacteria has been determined. Complementarity relationships between this sequence and a purine-rich tract in the ribosome binding site of different bacterial mRNAs suggest that the 3′-end of 16S RNA determines the intrinsic capacity of ribosomes to translate a particular cistron. 

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