Detergent sclerosants at sub-lytic concentrations induce endothelial cell apoptosis through a caspase dependent pathway

@article{CooleyAndrade2016DetergentSA,
  title={Detergent sclerosants at sub-lytic concentrations induce endothelial cell apoptosis through a caspase dependent pathway},
  author={Osvaldo Cooley-Andrade and Kelvin Cheung and An-Ning Chew and David Ewan Connor and Kurosh Parsi},
  journal={Apoptosis},
  year={2016},
  volume={21},
  pages={836-845}
}
To investigate the apoptotic effects of detergent sclerosants sodium tetradecylsulphate (STS) and polidocanol (POL) on endothelial cells at sub-lytic concentrations. Human umbilical vein endothelial cells (HUVECs) were isolated and labelled with antibodies to assess for apoptosis and examined with confocal microscopy and flow cytometry. Isolated HUVECs… CONTINUE READING