Detergent-salt resistance of LAP2alpha in interphase nuclei and phosphorylation-dependent association with chromosomes early in nuclear assembly implies functions in nuclear structure dynamics.

@article{Dechat1998DetergentsaltRO,
  title={Detergent-salt resistance of LAP2alpha in interphase nuclei and phosphorylation-dependent association with chromosomes early in nuclear assembly implies functions in nuclear structure dynamics.},
  author={Thomas Dechat and Josef Gotzmann and Andreas Stockinger and Crafford A. Harris and Mary Anne Talle and J. John Towaco Siekierka and Roland Foisner},
  journal={The EMBO journal},
  year={1998},
  volume={17 16},
  pages={
          4887-902
        }
}
Lamina-associated polypeptide (LAP) 2 of the inner nuclear membrane (now LAP2beta) and LAP2alpha are related proteins produced by alternative splicing, and contain a common 187 amino acid N-terminal domain. We show here that, unlike LAP2beta, LAP2alpha behaved like a nuclear non-membrane protein in subcellular fractionation studies and was localized throughout the nuclear interior in interphase cells. It co-fractionated with LAP2beta in nuclear lamina/matrix-enriched fractions upon extraction… CONTINUE READING

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References

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SHOWING 1-10 OF 74 REFERENCES

Structure mapping of the human thymopoeitin (TMPO) gene and relationship of human TMPO β to rat

  • C. A. Harris, P. J. Andryuk, S. W. Cline, S. Mathew, J. J. Siekiera, G. Goldstein
  • laminassociated polypeptide. Genomics,
  • 1995
Highly Influential
4 Excerpts

reveals a nuclear matrix - associated nucleolin complex of basic isoelectric point

  • C. A. Harris, P. J. Andryuk, +4 authors G. Goldstein
  • 1994
Highly Influential
8 Excerpts

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