Detergent-like actions of linear amphipathic cationic antimicrobial peptides.

@article{Bechinger2006DetergentlikeAO,
  title={Detergent-like actions of linear amphipathic cationic antimicrobial peptides.},
  author={Burkhard Bechinger and K. A. Lohner},
  journal={Biochimica et biophysica acta},
  year={2006},
  volume={1758 9},
  pages={1529-39}
}
Antimicrobial peptides have raised much interest as pathogens become resistant against conventional antibiotics. We review biophysical studies that have been performed to better understand the interactions of linear amphipathic cationic peptides such as magainins, cecropins, dermaseptin, delta-lysin or melittin. The amphipathic character of these peptides and their interactions with membranes resemble the properties of detergent molecules and analogies between membrane-active peptide and… CONTINUE READING
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