Detergent and detergent-free methods to define lipid rafts and caveolae.

  title={Detergent and detergent-free methods to define lipid rafts and caveolae.},
  author={Rennolds S. Ostrom and Xiaoqiu Liu},
  journal={Methods in molecular biology},
Lipid rafts and their related membrane vesicular structures, caveolae, are cholesterol- and sphingolipid-rich microdomains of the plasma membrane that have attracted considerable interest because of their ability to concentrate numerous signaling proteins. Efforts to define the proteins that reside in lipid rafts and caveolae as well as investigations into the functional role of these microdomains in signaling, endocytosis, and other cellular processes have led to the hypothesis that they… CONTINUE READING


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