Detection of widespread hepatocyte infection in chronic hepatitis C.

@article{Agnello1998DetectionOW,
  title={Detection of widespread hepatocyte infection in chronic hepatitis C.},
  author={Vincent Agnello and Gy{\"o}rgy Abel and Glenn B. Knight and E E Muchmore},
  journal={Hepatology},
  year={1998},
  volume={28 2},
  pages={573-84}
}
The controversial question of the extent of hepatocyte infection in chronic hepatitis C was re-examined in both chimpanzees and humans using a newly modified in situ hybridization (ISH) method for detecting hepatitis C virus (HCV) RNA. The specificity of the methodology for distinguishing positive- and negative-strand synthetic HCV RNA was at least six magnitudes greater than the reverse-transcription polymerase chain reaction (RT-PCR) assay for HCV. The sensitivity of the methodology as… CONTINUE READING
32 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

Similar Papers

Loading similar papers…