Detection of von Willebrand factor and tissue factor in platelets-fibrin rich coronary thrombi in acute myocardial infarction.

@article{Yamashita2006DetectionOV,
  title={Detection of von Willebrand factor and tissue factor in platelets-fibrin rich coronary thrombi in acute myocardial infarction.},
  author={Atsushi Yamashita and Takahiro Sumi and Shinya Goto and Yasunari Hoshiba and Kensaku Nishihira and Riichirou Kawamoto and Kinta Hatakeyama and Haruhiko Date and Takuroh Imamura and Hiroshi Ogawa and Yujiro Asada},
  journal={The American journal of cardiology},
  year={2006},
  volume={97 1},
  pages={
          26-8
        }
}
The rapid closure of coronary arteries due to occlusive thrombi is the major cause of acute myocardial infarction. However, the mechanisms of coronary thrombus formation have not been elucidated. We immunohistochemically assessed the localizations and their changes over time of glycoprotein IIb/IIIa, fibrin, von Willebrand factor (vWF), and tissue factor (TF), after the onset of chest pain (<4, 4 to 6, or 6 to 12 hours), in fresh coronary thrombi causing acute myocardial infarction. The… CONTINUE READING
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