Detection of vitamin C-induced singlet oxygen formation in oxidized LDL using MCLA as a chemiluminescence probe.

  • Juan Wang, Da Xing
  • Published 2002 in
    Sheng wu hua xue yu sheng wu wu li xue bao Acta…


In this study, it was observed that addition of vitamin C (vit C) to oxidized low-density lipoprotein (Ox-LDL) by cupric ions (Cu2+) could result in the formation of singlet oxygen (1O2). In experiments, 1O2 was detected by chemiluminescence method using a Cypridina luciferin analog, 2-methyl-6-(p-methoxyphenyl)-3, 7-dihydroimidazo [1, 2-a] pyrazin-3-one… (More)


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