Detection of viral DNA in neonatal herpes simplex virus infections: frequent and prolonged presence in serum and cerebrospinal fluid.

@article{Kimura1991DetectionOV,
  title={Detection of viral DNA in neonatal herpes simplex virus infections: frequent and prolonged presence in serum and cerebrospinal fluid.},
  author={Hiroki Kimura and Masahide Futamura and Hiroki Kito and Tamie Ando and Mieko Goto and Kiyotaka Kuzushima and Mari Shibata and Tsuneo Morishima},
  journal={The Journal of infectious diseases},
  year={1991},
  volume={164 2},
  pages={289-93}
}
Polymerase chain reaction (PCR) assay was used to detect herpes simplex virus (HSV) DNA in mouth, skin, sera, or cerebrospinal fluid (CSF) from seven neonates with HSV infection. In a culture-negative patient, the diagnosis was confirmed by detection of HSV DNA. Serial examinations revealed that HSV DNA remained in the serum and/or CSF from several patients for 1-2 weeks after the beginning of treatment. Next, the results of PCR assay in neonatal HSV infections were compared with those in older… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 54 extracted citations

Neonatal herpes simplex infection.

Clinical microbiology reviews • 2004
View 4 Excerpts
Highly Influenced

Herpes simplex virus.

Handbook of clinical neurology • 2014

Similar Papers

Loading similar papers…