Detection of vascular endothelial growth factor messenger RNA and vascular endothelial growth factor-like activity in proliferative diabetic retinopathy.

@article{Malecaze1994DetectionOV,
  title={Detection of vascular endothelial growth factor messenger RNA and vascular endothelial growth factor-like activity in proliferative diabetic retinopathy.},
  author={François J Malecaze and Simone Clamens and V Simorre-Pinatel and Armin Mathis and Philippe Chollet and Catherine Favard and Francis J Bayard and Jean Plou{\"e}t},
  journal={Archives of ophthalmology},
  year={1994},
  volume={112 11},
  pages={
          1476-82
        }
}
OBJECTIVE To study the involvement of eight angiogenic growth factors that have been identified so far in the literature, especially vascular endothelial growth factor, in proliferative diabetic retinopathy. METHODS Samples of neovascular membranes were obtained from diabetic patients; these samples, excised at vitrectomy, were used to study the expression of messenger RNA of the angiogenic factors by using the method of the reverse transcription-polymerase chain reaction. Vitreous aspirates… CONTINUE READING
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