Detection of varicella-zoster virus DNA by polymerase chain reaction in the cerebrospinal fluid of patients suffering from neurological complications associated with chicken pox or herpes zoster.

@article{PuchhammerStoeckl1991DetectionOV,
  title={Detection of varicella-zoster virus DNA by polymerase chain reaction in the cerebrospinal fluid of patients suffering from neurological complications associated with chicken pox or herpes zoster.},
  author={Elisabeth Puchhammer-Stoeckl and Therese Popow-Kraupp and Franz X Heinz and Christian W. Mandl and Christina Kunz},
  journal={Journal of clinical microbiology},
  year={1991},
  volume={29 7},
  pages={1513-6}
}
The polymerase chain reaction (PCR) was used to detect varicella-zoster virus (VZV) DNA in the cerebrospinal fluid of patients with VZV infection associated with neurological symptoms. Positive results were obtained in three of five children with post-chicken pox cerebellitis and in seven of seven herpes zoster patients with neurological symptoms. The PCR thus provides a useful tool for the early diagnosis of VZV-associated neurological disease.