Detection of type 2 diabetes related modules and genes based on epigenetic networks

@inproceedings{Liu2014DetectionOT,
  title={Detection of type 2 diabetes related modules and genes based on epigenetic networks},
  author={Hui Liu and Tongtong Wang and Hongbo Liu and Yanjun Wei and Guofeng Zhao and Jianzhong Su and Qiong Wu and Hong Qiao and Yan Zhang},
  booktitle={BMC Systems Biology},
  year={2014}
}
Type 2 diabetes (T2D) is one of the most common chronic metabolic diseases characterized by insulin resistance and the decrease of insulin secretion. Genetic variation can only explain part of the heritability of T2D, so there need new methods to detect the susceptibility genes of the disease. Epigenetics could establish the interface between the environmental factor and the T2D Pathological mechanism. Based on the network theory and by combining epigenetic characteristics with human… CONTINUE READING
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