Detection of tumor-specific cytotoxic drug activity in vitro using the fluorometric microculture cytotoxicity assay and primary cultures of tumor cells from patients.

Abstract

The semi-automated fluorometric microculture cytotoxicity assay (FMCA), based on the measurement of fluorescence generated from cellular hydrolysis of fluorescein diacetate (FDA) by viable cells, was employed for cytotoxic drug sensitivity testing of tumor cells from patients with hematological or solid tumors. In total, 390 samples from 20 diagnoses were… (More)

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@article{Nygren1994DetectionOT, title={Detection of tumor-specific cytotoxic drug activity in vitro using the fluorometric microculture cytotoxicity assay and primary cultures of tumor cells from patients.}, author={Peter Nygren and H. Fridborg and K. Csoka and Christer Sundstr{\"{o}m and Manuel de la Torre and Joergen U. Kristensen and Jonas Bergh and Hans Hagberg and Bengt Glimelius and Jonas Rastad}, journal={International journal of cancer}, year={1994}, volume={56 5}, pages={715-20} }