Detection of time-dependent and oxidatively induced antigens of bovine liver rhodanese with monoclonal antibodies.

@article{Merrill1988DetectionOT,
  title={Detection of time-dependent and oxidatively induced antigens of bovine liver rhodanese with monoclonal antibodies.},
  author={Gerald A Merrill and Paul M. Horowitz and Steve Bowman and Kevin L Bentley and Robert J. Klebe},
  journal={The Journal of biological chemistry},
  year={1988},
  volume={263 36},
  pages={19324-30}
}
Rhodanese has been extensively utilized as a model protein for the study of enzyme structure-function relationships. An immunological study of conformational changes occurring in rhodanese as a result of oxidation or thermal inactivation was conducted. Three monoclonal antibodies (MABs) to rhodanese were produced. Each MAB recognized a unique epitope as… CONTINUE READING