Detection of three common, deletional alpha-thalassemia determinants in Southern China by a single-tube multiplex polymerase chain reaction method.

@article{Liu2004DetectionOT,
  title={Detection of three common, deletional alpha-thalassemia determinants in Southern China by a single-tube multiplex polymerase chain reaction method.},
  author={Jing Liu and C. Y. Ou and Li Rong Wang and Bai Xiao and Li Huang and Li Chang Chen},
  journal={Hemoglobin},
  year={2004},
  volume={28 1},
  pages={39-44}
}
alpha-Thalassemia (thal) is one of the most common inherited disorders in the world and in Southern China. Three large deletions of the alpha-globin gene, namely the -alpha3.7 and -alpha4.2 (single gene deletions), and --SEA (Southeast Asian double gene deletion), are the main alpha-thal abnormalities in Southern China. We have developed a reliable, single… CONTINUE READING