Detection of the tumour-associated antigens recognized by the monoclonal antibodies HMFG-1 and 2 in serum from patients with breast cancer.

@article{Burchell1984DetectionOT,
  title={Detection of the tumour-associated antigens recognized by the monoclonal antibodies HMFG-1 and 2 in serum from patients with breast cancer.},
  author={Joy Burchell and De-kun Wang and Joyce Taylor-Papadimitriou},
  journal={International journal of cancer},
  year={1984},
  volume={34 6},
  pages={763-8}
}
The levels of the human milk fat globule 1 and 2 antigens have been measured in the sera of patients with advanced breast cancer, using a "sandwich" type radioimmune assay which exploits the carbohydrate nature of the antigenic determinants. In the series studied, 30% of sera from advanced breast cancer patients contained elevated levels of the HMFG-I antigen as compared with 6% of sera from healthy control women, whereas 53% of the advanced breast cancer patients showed elevated levels of HMFG… CONTINUE READING