Detection of the full-length transcript variant for neurokinin-1 receptor in human whole blood associated with enhanced reinforcement of clot by substance-P


We have recently reported that a neurotransmitter for pain, substance-P (SP), promotes platelet-dependent clot formation through neurokinin-1 receptors (NK1Rs), in which leukocytes appear to be involved (J Thromb Thrombolysis 2009;27:280–6). Two naturally occurring splice isoforms of NK1R with different signal transduction potency, namely the full-length… (More)
DOI: 10.1007/s11239-011-0650-1


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