Detection of the erythromycin rRNA methylase gene erm(A) in Enterococcus faecalis.

  title={Detection of the erythromycin rRNA methylase gene erm(A) in Enterococcus faecalis.},
  author={Karin Schwaiger and Johann Bauer},
  journal={Antimicrobial agents and chemotherapy},
  volume={52 8},
Erythromycin, a macrolide antibiotic, is used for the treatment of diseases caused by gram-positive bacteria (7). Resistance to macrolides, lincosamides, and streptogramin B in many isolates is due to so-called erm genes, encoding RNA methylases (6). Several classes of rRNA methylases in grampositive cocci, in Bacillus spp., and in erythromycin-producing actinomycetes have been identified previously (1, 10). However, the detection of erm(A) in Enterococcus faecalis has not been reported to date… CONTINUE READING


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