Detection of swine-origin influenza A (H1N1) viruses using a localized surface plasmon coupled fluorescence fiber-optic biosensor.

@article{Chang2010DetectionOS,
  title={Detection of swine-origin influenza A (H1N1) viruses using a localized surface plasmon coupled fluorescence fiber-optic biosensor.},
  author={Ying-Feng Chang and Sheng-Fan Wang and Jason C. Huang and Li-Chen Su and Ling Yao and Ying-Chang Li and Suh-Chin Wu and Yi-Ming Arthur Chen and Jo-Ping Hsieh and Chien Chou},
  journal={Biosensors & bioelectronics},
  year={2010},
  volume={26 3},
  pages={1068-73}
}
Swine-origin influenza A (H1N1) virus (S-OIV) was identified as a new reassortant strain of influenza A virus in April 2009 and led to an influenza pandemic. Accurate and timely diagnoses are crucial for the control of influenza disease. We developed a localized surface plasmon coupled fluorescence fiber-optic biosensor (LSPCF-FOB) which combines a sandwich immunoassay with the LSP technique using antibodies against the hemagglutinin (HA) proteins of S-OIVs. The detection limit of the LSPCF-FOB… CONTINUE READING
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